Search results for " causes"

showing 10 items of 35 documents

Estimating Global Burden of Disease due to congenital anomaly: an analysis of European data

2017

ObjectiveTo validate the estimates of Global Burden of Disease (GBD) due to congenital anomaly for Europe by comparing infant mortality data collected by EUROCAT registries with the WHO Mortality Database, and by assessing the significance of stillbirths and terminations of pregnancy for fetal anomaly (TOPFA) in the interpretation of infant mortality statistics.Design, setting and outcome measuresEUROCAT is a network of congenital anomaly registries collecting data on live births, fetal deaths from 20 weeks’ gestation and TOPFA. Data from 29 registries in 19 countries were analysed for 2005–2009, and infant mortality (deaths of live births at age <1 year) compared with the WHO Mortality …

0301 basic medicineMalePediatrics030105 genetics & heredityInfant DeathGlobal Burden of Disease0302 clinical medicineCongenital anomaly ; DALY ; Global Burden of Disease ; YLL ; mortality.PregnancyPrenatal DiagnosisYLLEpidemiologyInfant MortalityPrevalenceMedicineEPIDEMIOLOGY030212 general & internal medicineRegistries1506DOWN-SYNDROMEPOPULATIONeducation.field_of_studyDALYAnomaly (natural sciences)Pregnancy OutcomeObstetrics and GynecologyGestational ageGeneral MedicineStillbirthUPDATED SYSTEMATIC ANALYSISPREVALENCEEuropeFetal Mortality/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemaleOriginal ArticleCHILD-MORTALITYAdultCOUNTRIESmedicine.medical_specialtyPopulationGestational AgeCongenital Abnormalities03 medical and health sciencesSDG 3 - Good Health and Well-beingJournal ArticleHumansCongenital anomalyAbortion Induced/statistics & numerical data; Adult; Congenital Abnormalities/diagnosis; Congenital Abnormalities/epidemiology; Europe/epidemiology; Female; Fetal Death/prevention & control; Fetal Mortality; Gestational Age; Global Burden of Disease/methods; Global Burden of Disease/statistics & numerical data; Humans; Infant; Infant Death/prevention & control; Infant Mortality; Infant Newborn; Male; Pregnancy; Pregnancy Outcome/epidemiology; Prenatal Diagnosis/methods; Prenatal Diagnosis/statistics & numerical data; Prevalence; Registries/statistics & numerical data; Stillbirth/epidemiology; Congenital anomaly; DALY; Global Burden of Disease; YLL; mortalityeducationFetal DeathPregnancybusiness.industryInfant NewbornInfantAbortion InducedNATIONAL CAUSESmedicine.diseasemortalityTRENDSInfant mortalityChild mortalityYears of potential life lostPediatrics Perinatology and Child HealthbusinessPRIMARY PREVENTIONDemography
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Les drogodependències, una visió actualitzada

2013

Public opinion is not worried about drug dependence and other addictive disorders anymore. The changes in consumption patterns and the lack of visible situations related to drugs consumption have removed this problem from the top of the media’s agenda; however, we are able to establish that this is not a settled problem from the past, but quite the opposite. Despite all the prevention campaigns launched so far, the drugs consumption phenomenon prevails as well as the increase of the number of admissions in detoxification clinics for drug addicts. Therefore, it would be necessary to make a review of the history of drug dependence in order to find the key of the causes thereof nowadays, putti…

:SOCIOLOGÍA::Cambio y desarrollo social [UNESCO]Drogodependències interés premsa prevalencia causes adolescència. Drug dependence interest the media prevalence causes adolescence. ArtículoUNESCO::SOCIOLOGÍA::Cambio y desarrollo social
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Ricerche in tema di società questuarie

2019

Intorno al regime delle società di tipo questuario – riconducibili agli schemi teorici della societas universorum quae ex quaestu veniunt – e delle società unius alicuius negotiationis e unius rei, si profusero gli sforzi interpretativi dei giuristi romani, fin dalla fine dell’età repubblicana. La monografia scientifica ripercorre le tracce della individuazione della nozione stessa di quaestus (guadagno), con particolare riferimento alla inclusione al suo interno delle donazioni cd. remuneratorie; ancora, ricostruisce il dibattito giurisprudenziale sorto intorno alla questione se i soci – nella determinazione delle quote – dovessero rispettare una proporzione rispetto ai conferimenti, con u…

About the regulations of the societas quaestus - referable to the societas universorum quae ex quaestu veniunt and to the societas unius alicuius negotiationis and unius rei - the interpretative efforts of the Roman jurists were given profusely since the end of the republican age. The scientific monograph puts itself on the traces of identifying the notion of quaestus (gain) with particular reference to the inclusion within it of the so-called remuneration gifts. Furthermore it reconstructs the jurisprudential debate that aroses around the question of whether the socii - in the determination of the shares - had to respect a proportion with the contributions and in this sense with an attempt to explain the existing contrast between a passage from the Digest and one of the Iustiniani Institutiones. Moreover always with specific reference to the societas quaestus the monograph investigates the setting-up of the intempestiva renuntiatio supporting its origin out of the contrast between Proculiani and Sabiniani so far postulated in doctrine. Finally the book closes with a chapter dedicated to the genesis of the term egestas which appears in a fragment of Modestinus (D. 17.2.4.1) dedicated to the causes of dissolution of the societas consensu contractaSettore IUS/18 - Diritto Romano E Diritti Dell'Antichita'
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The role of punishment in the works of Adam Smith

2009

The reformation of criminal justice is one of the great themes in Enlightenment culture and concerned its main exponents from Montesquieu to Beccaria, Filangieri, Bentham. One of the traits of greater modernity in the theories worked out by juridical Enlightenment is the resort to the utilitarianinspired economic analysis. Adam Smith doesn't back out of this scientific and civil commitment, but his doctrine appears significantly different though contemporary to juridical Enlightenment, and is also based on economic argumentations. In this work we will look through the main writings which contain the Smithian thought in search of those parts dealing with the theme of punishment and its socia…

Adam Smith Theory Of Moral Sentiments Glasgow Lectures An Enquiry Into The Nature And Causes Of The Wealth Of Nations Scottish Enlightenment Punishment Natural law Utilitarianism economic analysis of law. JEL classification codes: B11 B31 K14Settore SECS-P/04 - Storia Del Pensiero Economico
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Impact of era of diagnosis on cause-specific late mortality among 77 423 five-year European survivors of childhood and adolescent cancer:The PanCareS…

2022

Late mortality of European five-year survivors of childhood or adolescent cancer has dropped over the last 60 years, but excess mortality persists. There is little information concerning secular trends in cause-specific mortality among older European survivors. PanCareSurFup pooled data from 12 cancer registries and clinics in 11 European countries from 77 423 five-year survivors of cancer diagnosed before age 21 between 1940 to 2008 followed for an average age of 21 years and a total of 1.27 million person-years to determine their risk of death using cumulative mortality, standardized mortality ratios (SMR), absolute excess risks (AER), and multivariable proportional hazards regression ana…

AdultMaleCancer ResearchSecond NeoplasmsAdolescentAdolescent cancercauses of deathEuropean03 medical and health sciencesYoung Adult0302 clinical medicineCancer SurvivorsCause of DeathMedicineHumans030212 general & internal medicineCause specificChild610 Medicine & healthAgedExcess mortalitybusiness.industrycardiovascularsecond malignant neoplasmsHazard ratioCancersurvivors of childhood cancerMiddle Agedmedicine.diseaseConfidence interval3. Good healthOncologyEuropean; cardiovascular; causes of death; late mortality; second malignant neoplasms; survivors of childhood cancer030220 oncology & carcinogenesisChild Preschoollate mortalityFemaleRisk of deathbusiness360 Social problems & social servicesDemography
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Analysis of thiamine transporter genes in sporadic beriberi

2014

Abstract Objective Thiamine or vitamin B 1 deficiency diminishes thiamine-dependent enzymatic activity, alters mitochondrial function, impairs oxidative metabolism, and causes selective neuronal death. We analyzed for the first time, the role of all known mutations within three specific thiamine carrier genes, SLC19 A2, SLC19 A3 , and SLC25 A19 , in a patient with atrophic beriberi, a multiorgan nutritional disease caused by thiamine deficiency. Methods A 44-year-old male alcoholic patient from Morocco developed massive bilateral leg edema, a subacute sensorimotor neuropathy, and incontinence. Despite normal vitamin B 1 serum levels, his clinical picture was rapidly reverted by high-dose in…

AdultMalemedicine.medical_specialtySLC19 A- SLC25 A19SLC19 AEndocrinology Diabetes and MetabolismGene mutationBeriberimedicine.disease_causeMitochondrial Membrane Transport Proteinslaw.inventionBeriberilawInternal medicineGenotypemedicineThiamine transporterObjective: Thiamine or vitamin B1 deficiency diminishes thiamine-dependent enzymatic activity alters mitochondrial function impairs oxidative metabolism and causes selective neuronal death. We analyzed for the first time the role of all known mutations within three specific thiamine carrier genes SLC19 A2 SLC19 A3 and SLC25 A19 in a patient with atrophic beriberi a multiorgan nutritional disease caused by thiamine deficiency. Methods: A 44-year-old male alcoholic patient from Morocco developed massive bilateral leg edema a subacute sensorimotor neuropathy and incontinence. Despite normal vitamin B1 serum levels his clinical picture was rapidly reverted by high-dose intramuscular thiamine treatment suggesting a possible genetic resistance. We used polymerase chain reaction followed by amplicon sequencing to study all the known thiamine-related gene mutations identified within the Human Gene Mutation Database. Results: Thirty-seven mutations were tested: 29 in SLC19 A2 6 in SLC19 A3 and 2 in SLC25 A19. Mutational analyses showed a wild-type genotype for all sequences investigated. Conclusion: This is the first genetic study in beriberi disease. We did not detect any known mutation in any of the three genes in a sporadic dry beriberi patient. We cannot exclude a role for other known or unknown mutations in the same genes or in other thiamine-associated genes in the occurrence of this nutritional neuropathy.HumansThiamineGenePolymerase chain reactionGeneticsMutationNutrition and DieteticsbiologyMembrane Transport ProteinsThiamine Deficiencymedicine.diseaseAlcoholismEndocrinologyMutationbiology.proteinThiamineMutations
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La conception subjective de l'objet de l'obligation de révélation de l'arbitre

2015

International audience; (Civ. 1re, 18 décembre 2014, n° 14-11.085), VR services c/ Soc. Dukan de Nitya, D. 2015. 86, à paraître au Bulletin)

Arbitre[SHS.DROIT]Humanities and Social Sciences/LawRévélation des causes possibles de récusation[SHS.DROIT] Humanities and Social Sciences/LawArbitrage interneARBITRAGEConception subjective
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Arbitres. Obligation de révéler les causes possibles de récusation, Sanction de l'inexécution de cette obligation, Violation des droits de la défense…

1995

International audience; (Paris, 1re ch., 23 mars 1995, inédit, Soc. Maec SA, Soc. Domiticom Sarl c/ P. Mumbach)

Arbitre[SHS.DROIT]Humanities and Social Sciences/LawRévélation des causes possibles de récusation[SHS.DROIT] Humanities and Social Sciences/LawArbitrage interneARBITRAGESanction de l'inexécution de cette obligation
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Polybe et Montesquieu : aspects d’une réflexion sur le pouvoir 1

2012

Dans la préparation à l’Esprit des Lois que sont les Considérations sur les causes de la grandeur des Romains et de leur décadence, Montesquieu se réfère, entre autres sources, aux Histoires de Polybe. Si les deux auteurs ont des méthodes différentes pour établir les faits, ni l’un ni l’autre ne proposent cependant à leur lecteur une simple relation de l’histoire de Rome : Polybe veut que ses Histoires forment les responsables politiques et les Considérations sont, selon d’Alembert, une “ histoire romaine à l’usage des hommes d’État et des philosophes ”. Tous deux conduisent donc, à partir de l’exemple romain, une réflexion plus large sur la nature du pouvoir, les conditions de sa conquête …

Considérations sur les causes de la grandeur des Romains et de leur décadenceconquêtephilosophie politiqueGeneral Medicineconstitution mixtePolybeAnacyclosePolybusconquestpolitical philosophyhegemonyAnacyclosismixed constitutionhégémonieMontesquieuAnabases
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Measuring the shadow economy and its drivers: the case of peripheral EMU countries

2019

We adopt a long-run perspective to investigate the size of the shadow economy and explore the trends in this area. The analysis is based on a panel of peripheral EMU countries over the period 1965-2015. Our empirical approach relies on a multiple indicators and multiple causes (MIMIC) framework. This approach is a variant of structural equation modelling (SEM). We used two sets of variables, (i.e. potential determinants and indicator variables) to estimate an underlying (unobserved) index that measures the evolution of the shadow economy. Ascertaining the relative importance of the shadow economy enabled analysis of its relationship with other institutional and social issues (e.g. corruptio…

Economics and Econometricseuropean economic and monetary unionPerspective (graphical)structural equation modellinglcsh:Regional economics. Space in economicslcsh:HD72-88lcsh:HT388lcsh:Economic growth development planningShadow economy; structural equation modelling; multiple indicators multiple causes models; European Economic and Monetary Unionshadow economyEconomyEconomicsmultiple indicators multiple causes modelsShadow (psychology)Ekonomska Istraživanja
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